The Cathedral is dedicated to Saint Florido and Saint Amanzio. In over a thousand years it has been consecrated three times. It is said that the first cathedral was built on the ruins of a pagan temple by the young Pliny, the patron of Tifernum Tiberinum, that is, Città di Castello. It was Bishop Florido (ca. 520 – 600) who encouraged the citizens to rebuild the town and the cathedral after the Goths had destroyed everything. The cathedral took the name of San Lorenzo. In 1032 Bishop Pietro consecrated a second cathedral and dedicated it to Saint Florido and Saint Amanzio the patron saints of the town and diocese. That is when the round bell tower was added. In 1356 the tombs and reliquaries of the patron saints were discovered and the population enthusiastically threw itself into reconstruction.